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BNIP3L Monoclonal Antibody (ZN002), Invitrogen™
Mouse Monoclonal Antibody
Supplier: Invitrogen 393300
Description
Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro apoptotic proteins, including Bad, Bax, Bid, Bik, Hrk, Nip3, and Bim, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bnip3L, Bnip3a, and Nix (for Nip3-like protein X Bnip3L/Bnip3a/Nix is a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Bnip3. Overexpression of Bnip3L induces apoptosis. Bnip3L interacts with and overcomes suppresses by Bcl-2 and Bcl-xL. Bnip3L is localized in mitochondria.Specifications
| BNIP3L | |
| Monoclonal | |
| 0.5 mg/mL | |
| BNIP3L | |
| BNIP3a, NIX, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A, BCL2/adenovirus E1B 19-kd protein-interacting protein 3a, NIP3-like protein X, NIP3L, adenovirus E1B19k-binding protein B5 | |
| Mouse | |
| Protein A | |
| RUO | |
| 12177, 665 | |
| -20°C | |
| Liquid |
| ELISA, Immunocytochemistry, Immunofluorescence, Western Blot | |
| ZN002 | |
| Unconjugated | |
| O60238, Q9Z2F7 | |
| BNIP3L | |
| Synthetic peptide derived from the internal region of human, mouse and rat Nix proteins | |
| 100 μg | |
| Primary | |
| Human, Mouse, Non-human Primate | |
| Antibody | |
| IgG1 κ |
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